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Aladdin阿拉丁 N-乙酰基-L-α-天冬氨酰-L-α-谷氨酰-L-缬氨酰-N-(4-硝基苯基)-L-天冬氨酰胺 CAS : 189950-66-1 N133165
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NAc-Asp-Glu-Val-Asp-pNA;Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) (Km=9.7μM) and related cysteine proteases. It is also a substrate for caspase-6, caspase-7, caspase-8, and caspase-10. The sequence is based on PARP (poly(ADPribose) polymerase) cleavage site Asp216 for caspase-3. Cleavage is monitored colorimetrically at 405nm.A colorimetric substrate for caspase-3 (CPP32) and related cysteine proteases NAc-Asp-Glu-Val-Asp-pNA;Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) (Km=9.7μM) and related cysteine proteases. It is also a substrate for caspase-6, caspase-7, caspase-8, and caspase-10. The sequence is based on PARP (poly(ADPribose) polymerase) cleavage site Asp216 for caspase-3. Cleavage is monitored colorimetrically at 405nm. A colorimetric substrate for caspase-3 (CPP32) and related cysteine proteases
产品名称 N-乙酰基-L-α-天冬氨酰-L-α-谷氨酰-L-缬氨酰-N-(4-硝基苯基)-L-天冬氨酰胺 产品名称 N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide 别名 Ac-DEVD-pNA;N-乙酰基-Asp-Glu-Val-Asp p-硝基苯胺 CAS编号 189950-66-1 分子式 C26H34N6O13 分子量 638.58 MDL号 MFCD00792707 规格或纯度 ≥97%(HPLC) 应用 A colorimetric substrate for caspase-3 (CPP32) and related cysteine proteases 生化机理 Colorimetric substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase. 溶解性 Soluble in water (partly), DMSO, buffer, pH 7, and acetonitrile:methanol (1:1) (1 mg/ml). 储存温度储存温度-20°C 品牌阿拉丁
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