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BD Pharmingen™ APC-Cy™7 Rat Anti-Mouse CD45 561037
- 品 牌：BD Pharmingen
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BD Pharmingen™ APC-Cy™7 Rat Anti-Mouse CD45 561037，克隆 30-F11 (RUO)
BD Pharmingen™ APC-Cy™7 Rat Anti-Mouse CD45 561037
克隆:
30-F11
尺寸:
25 µg
状态:
RUO
品类编号:
561037
荧光素标记
APC-Cy7
抗原名称
CD45
宿主
Rat LOU, also known as Louvain, LOU/C, LOU/M IgG2b, κ
免疫原
Mouse Thymus / Spleen
别名
Ptprc; LCA; Leukocyte common antigen; T200; Ly-5; Lyt-4
BD Pharmingen™ APC-Cy™7 Rat Anti-Mouse CD45 561037
抗体详情
30-F11
The 30-F11 clone has been reported to react with all isoforms and both alloantigens of CD45, which is found on hematopoietic stem cells and all cells of hematopoietic origin, except erythrocytes. CD45 is a transmembrane glycoprotein which is expressed at high levels on the cell surface, and its presence distinguishes leukocytes from non-hematopoietic cells. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family, where the intracellular carboxy-terminal region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated as A, B, and C, respectively). CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction and the CD45 isoforms detected in the mouse are cell type-, maturation-, and activation state-specific.
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